The Hidden Struggles of Entrepreneurship: Mental Health, Human Challenges, and Building Resilience
- Erdinc Ekinci
- 3 days ago
- 3 min read
Recently, I had the privilege of hosting an event titled “Human Side of Entrepreneurship: Lessons from 8K Startups + Open Mic Session” at Venture Café. It was a moment that reminded me why I love this ecosystem so much—not for the headlines or funding numbers, but for the raw, honest stories of founders navigating the rollercoaster of building something meaningful.

Hosting this session allowed me to engage directly with founders, investors, and mentors, hearing firsthand the challenges, doubts, and triumphs that aren’t captured in glossy articles or investor decks. From mental health struggles and decision fatigue to moments of inspiration and breakthrough, the discussion highlighted a side of entrepreneurship that’s rarely addressed openly: the deeply human experience behind building a startup.
The event also featured an open mic session, giving founders the chance to share their personal journeys, lessons learned, and fears in a safe, supportive space. It was inspiring to see people candidly discuss both failures and successes, revealing the resilience, creativity, and emotional intelligence required to keep moving forward in uncertain times.
Watch the full video here-
The Hidden Struggles of Founders
One of the recurring themes during the session was isolation. Even surrounded by teams, founders often feel alone in making decisions that could make or break their company. The pressure to appear confident and capable, even when uncertain, can be overwhelming.
“Sometimes it feels like everyone expects you to have all the answers, but no one talks about the emotional toll it actually takes,” one founder shared during the open mic session.
This honesty sparked a deeper conversation about mental health in entrepreneurship. Stress, anxiety, burnout, and imposter syndrome aren’t abstract—they’re real experiences that impact every decision, interaction, and strategy.
Why Mental Health Matters
Some statistics shared during the discussion highlighted the scale of the challenge:
72% of startup founders report that their role negatively impacts their mental health.
37% experience anxiety, while 54% report burnout in the first year.
Founders’ mental health strain is five times higher than the general population.
Acknowledging these realities is crucial—not only for the well-being of founders themselves but also for building sustainable companies.
Challenges Often Left Unspoken
During the session, several common yet unspoken challenges surfaced:
Decision fatigue: Constantly juggling priorities across product, team, investors, and personal life.
Fear of rejection: Hearing “no” from investors, customers, or mentors can feel personal.
Comparison traps: Seeing peers’ progress can heighten self-doubt.
Guilt and imposter syndrome: Many founders struggle with feeling undeserving of their achievements.
Entrepreneurship is as much an emotional journey as it is a business one. Recognizing this reality is the first step toward building resilience.
Building Resilience: Insights from Startup Life
Founders often shared actionable strategies for navigating the mental and emotional challenges of entrepreneurship:
Prioritize self-care: Exercise, sleep, and mindfulness are essential for sustaining energy and focus.
Break down tasks: Tackling small, incremental goals helps reduce overwhelm and maintain momentum.
Protect relationships: Time with family and friends is crucial for balance and perspective.
Reframe rejection: Viewing “no” as feedback rather than failure allows continuous learning.
Face fear intentionally: Real growth often lies just beyond discomfort.
Avoid burnout: Setting boundaries and scheduling downtime safeguards long-term productivity.
Stop comparing: Focusing on your own progress rather than others’ keeps motivation grounded.
Simplify decision-making: Automating repetitive tasks frees up mental bandwidth for high-impact choices.
The Power of Community
One of the highlights of the event was witnessing the impact of community and mentorship. Founders thrived when they had spaces to share struggles, learn from peers, and receive guidance from experienced entrepreneurs. Support networks aren’t just helpful—they are essential for sustainable growth.
Takeaways from Hosting
Hosting this session reminded me that entrepreneurship is far more than numbers, growth charts, or exits. It’s about navigating uncertainty with resilience, self-awareness, and empathy. True success includes both business achievements and the ability to maintain well-being while building something meaningful.
As one participant aptly shared during the open mic:
“You can’t pour from an empty cup. Taking care of yourself isn’t optional—it’s part of building a successful startup.”




